2017 – Hemi-Synthesis and Anti-Oomycete Activity of Analogues of Isocordoin

An efficient synthesis of a series of 4?-oxyalkyl-isocordoin analogues (2–8) is reported for the first time. Their structures were confirmed by 1H-NMR, 13C-NMR, and HRMS. Their anti-oomycete activity was evaluated by mycelium and spores inhibition assay against two selected pathogenic oomycetes strains: Saprolegnia parasitica and Saprolegnia australis. The entire series of isocordoin derivatives (except compound 7) showed high inhibitory activity against Leer más2017 – Hemi-Synthesis and Anti-Oomycete Activity of Analogues of Isocordoin[…]

2017 – Biological and antioxidant activity of Gunnera tinctoria (Nalca)

The endemic Chilean edible plant Gunnera tinctoria (Nalca) is highly appreciated in the south of Chile by the small farmers. Nevertheless, no background exists about his secondary metabolites. In the present study, in the leaf from G. tinctoria was investigated the content of bioactive compounds like coumaric acid, ascorbic acid and total phenols; the antioxidant Leer más2017 – Biological and antioxidant activity of Gunnera tinctoria (Nalca)[…]

2017 – Recuento en saliva de Streptococcus mutans en niños de 6 a 12 años con y sin tinciones cromógenas

Introducción: Las tinciones cromógenas o “Black Stain” (BS) se han asociado a una baja experiencia de caries y un menor recuento de bacterias cariogénicas. El objetivo es determinar si existe diferencia en el número de pacientes que presenten un alto recuento de S. mutans (>105 UFC/ml saliva) entre niños con BS y sin ellas.  Material y métodos: Estudio observacional analítico Leer más2017 – Recuento en saliva de Streptococcus mutans en niños de 6 a 12 años con y sin tinciones cromógenas[…]

2016 – In Vitro Antimicrobial Activity of Embothrium coccineum Used as Traditional Medicine in Patagonia against Multiresistant Bacteria

Embothrium coccineum J.R. Forst. & G. Forst is an evergreen tree that has been used as a folk remedy for the treatment of neuralgia, tooth pains, wound healing, and glandular conditions, as well as an antiseptic agent against bacterial infection. The antibacterial activities of sequential extracts (hexane, dichloromethane, ethyl acetate, and ethanol) from the leaves of E. Leer más2016 – In Vitro Antimicrobial Activity of Embothrium coccineum Used as Traditional Medicine in Patagonia against Multiresistant Bacteria[…]

2016 – Detección de virus parainfluenza en pacientes inmunocomprometidos e inmunocompetentes atendidos en un hospital terciario de la Ciudad de São Paulo, Brasil

Se evaluó la infección por virus parainfluenza (VPI) en pacientes con infecciones leves y graves mediante RPC en tiempo real. Se analizó un total de 1.067 muestras: 233 provenían de pacientes ambulatorios adultos receptores de trasplantes renales, 129 de niños con cardiopatía congénita, 381 de pacientes receptores de trasplantes de precursores hematopoyéticos adultos y 324 Leer más2016 – Detección de virus parainfluenza en pacientes inmunocomprometidos e inmunocompetentes atendidos en un hospital terciario de la Ciudad de São Paulo, Brasil[…]

2016 – Hongos Productores de Micotoxinas Asociados a Hierbas Medicinales en la Ciudad de São Paulo, Brasil

Antecedentes: La fitoterapia es una de las más antiguas prácticas utilizadas por la humanidad. Hasta mediados del siglo XIX, cuando se introdujeron los medicamentos, la formulación de estos generalmente era basada en plantas medicinales. Objetivos: Determinar la micobiota y los niveles de aflatoxinas originadas de Aspergillus sección Flavi aislados de las 50 muestras de medicamentos fitoterápicos comercializados actualmente en la ciudad Leer más2016 – Hongos Productores de Micotoxinas Asociados a Hierbas Medicinales en la Ciudad de São Paulo, Brasil[…]

2016 – The Chilean Network of Microbial Culture Collections: Establishment and Operation

According to the data available at the World Data Center for Microorganism-WDCM from the Word Federation for Culture Collection-WFCC, Chile has four registered culture collections that preserve 2777 microbial strains. At the global point of view, the culture collections in Chile are in different level of operation regarding its own infrastructure and compliancy with quality Leer más2016 – The Chilean Network of Microbial Culture Collections: Establishment and Operation[…]

2016 – Synthesis and Evaluation of Novel Oxyalkylated Derivatives of 2′,4′-Dihydroxychalcone as Anti-Oomycete Agents against Bronopol Resistant Strains of Saprolegnia sp.

A series of novel oxyalkylchalcones substituted with alkyl groups were designed and synthesized, and the antioomycete activity of the series was evaluated in vitro against Saprolegnia strains. All tested O-alkylchalcones were synthesized by means of nucleophilic substitution from the natural compound 2′,4′-dihydroxychalcone (1) and the respective alkyl bromide. The natural chalcone (1) and 10 synthetic oxyalkylchalcones (2–11) were Leer más2016 – Synthesis and Evaluation of Novel Oxyalkylated Derivatives of 2′,4′-Dihydroxychalcone as Anti-Oomycete Agents against Bronopol Resistant Strains of Saprolegnia sp.[…]

2015 – Un caso de queratitis micótica por Fusarium solani en Valdivia, Chile

La queratitis micótica es una de las principales infecciones oculares. Se necesita un tratamiento específico que depende de la naturaleza del microorganismo infectante. Su pronóstico suele ser grave y depende de un diagnóstico precoz y una terapia adecuada. Artículo completo en Revista Iberoamericana de Micología     

2015 – Chemical Characterization and Anti-Oomycete Activity of Laureliopsis philippianna Essential Oils against Saprolegnia parasitica and S. australis

Laureliopsis philippiana (Looser) R. Schodde (Monimiaceae) is a native tree widespread in the forest areas in the south of Chile and Argentina, known for its medicinal properties and excellent wood. The aim of this study was to evaluate the chemical composition of L. philippiana leaf and bark essential oils (EOs) using gas chromatography-mass spectrometry (GC-MS), and to quantify Leer más2015 – Chemical Characterization and Anti-Oomycete Activity of Laureliopsis philippianna Essential Oils against Saprolegnia parasitica and S. australis[…]