2016 – Hongos Productores de Micotoxinas Asociados a Hierbas Medicinales en la Ciudad de São Paulo, Brasil

Antecedentes: La fitoterapia es una de las más antiguas prácticas utilizadas por la humanidad. Hasta mediados del siglo XIX, cuando se introdujeron los medicamentos, la formulación de estos generalmente era basada en plantas medicinales. Objetivos: Determinar la micobiota y los niveles de aflatoxinas originadas de Aspergillus sección Flavi aislados de las 50 muestras de medicamentos fitoterápicos comercializados actualmente en la ciudad Leer más2016 – Hongos Productores de Micotoxinas Asociados a Hierbas Medicinales en la Ciudad de São Paulo, Brasil[…]

2016 – The Chilean Network of Microbial Culture Collections: Establishment and Operation

According to the data available at the World Data Center for Microorganism-WDCM from the Word Federation for Culture Collection-WFCC, Chile has four registered culture collections that preserve 2777 microbial strains. At the global point of view, the culture collections in Chile are in different level of operation regarding its own infrastructure and compliancy with quality Leer más2016 – The Chilean Network of Microbial Culture Collections: Establishment and Operation[…]

2016 – Synthesis and Evaluation of Novel Oxyalkylated Derivatives of 2′,4′-Dihydroxychalcone as Anti-Oomycete Agents against Bronopol Resistant Strains of Saprolegnia sp.

A series of novel oxyalkylchalcones substituted with alkyl groups were designed and synthesized, and the antioomycete activity of the series was evaluated in vitro against Saprolegnia strains. All tested O-alkylchalcones were synthesized by means of nucleophilic substitution from the natural compound 2′,4′-dihydroxychalcone (1) and the respective alkyl bromide. The natural chalcone (1) and 10 synthetic oxyalkylchalcones (2–11) were Leer más2016 – Synthesis and Evaluation of Novel Oxyalkylated Derivatives of 2′,4′-Dihydroxychalcone as Anti-Oomycete Agents against Bronopol Resistant Strains of Saprolegnia sp.[…]

2015 – Un caso de queratitis micótica por Fusarium solani en Valdivia, Chile

La queratitis micótica es una de las principales infecciones oculares. Se necesita un tratamiento específico que depende de la naturaleza del microorganismo infectante. Su pronóstico suele ser grave y depende de un diagnóstico precoz y una terapia adecuada. Artículo completo en Revista Iberoamericana de Micología     

2015 – Chemical Characterization and Anti-Oomycete Activity of Laureliopsis philippianna Essential Oils against Saprolegnia parasitica and S. australis

Laureliopsis philippiana (Looser) R. Schodde (Monimiaceae) is a native tree widespread in the forest areas in the south of Chile and Argentina, known for its medicinal properties and excellent wood. The aim of this study was to evaluate the chemical composition of L. philippiana leaf and bark essential oils (EOs) using gas chromatography-mass spectrometry (GC-MS), and to quantify Leer más2015 – Chemical Characterization and Anti-Oomycete Activity of Laureliopsis philippianna Essential Oils against Saprolegnia parasitica and S. australis[…]

2014 – Synthesis and antifungal activity of phenacyl azoles

A new N-(4-methoxyphenacyl)imidazole and three new substituted N-(phenacyl)triazoles were prepared by reaction of the heterocycle with a phenacyl halide. The former ketone and one example of the latter were reduced to the corresponding alcohols. All six compounds were screened in vitro for antifungal activity against two pathogenic fungal strains, Candida albicans (fluconazole-resistant) and Aspergillus fumigatus. The results revealed that most of the compounds showed activity Leer más2014 – Synthesis and antifungal activity of phenacyl azoles[…]

2014 – Feohifomicosis causada por Colletotrichum gloeosporioides y Alternaria infectoria en un paciente trasplantado renal

Diversas especies de hongos negros han sido descritos como agentes de feohifomicosis subcutáneas. A pesar que la gran mayoría de estos se consideran como oportunistas, juegan un papel importante en la feohifomicosis, enfermedad considerada una micosis emergente en pacientes trasplantados de órganos sólidos. Reportamos un caso de feohifomicosis subcutánea causada por Alternaria infectoria en el dorso de Leer más2014 – Feohifomicosis causada por Colletotrichum gloeosporioides y Alternaria infectoria en un paciente trasplantado renal[…]

2014 – Yeasts isolated from nosocomial urinary infections Antifungal susceptibility and biofilm production

Background: Urinary Candida infections in the hospital environment are frequent and need to be betterunderstood.Aims: To compare the results of antifungal susceptibility profiles of yeasts isolated from patients withurinary infections obtained by broth microdilution method (BM) and by disk diffusion (DD), and alsoevaluate the capacity of these yeasts to form biofilms.Methods: Only yeasts obtained from Leer más2014 – Yeasts isolated from nosocomial urinary infections Antifungal susceptibility and biofilm production[…]

2013 – The water supply system as a potential source of fungal infection in paediatric haematopoietic stem cell units

BACKGROUND: We conducted a prospective study to investigate the presence of microfungal contamination in the water supply system of the Oncology Paediatric Institute, São Paulo-Brazil after the occurrence of one invasive Fusarium solani infection in a patient after Haematopoietic Stem Cell Transplantation (HSCT). During a twelve-month period, we investigated the water supply system of the Leer más2013 – The water supply system as a potential source of fungal infection in paediatric haematopoietic stem cell units[…]

2012 – Molecular phylogeny and phenotypic variability of clinical and environmental strains of Aspergillus flavus

Aspergillus flavus is the second most common cause of aspergillosis infection in immunocompromised patients and is responsible for the production of aflatoxins. Little is known about the population structure of A. flavus, although recent molecular and phenotypic data seem to demonstrate that different genetic lineages exist within this species. The aim of this study was Leer más2012 – Molecular phylogeny and phenotypic variability of clinical and environmental strains of Aspergillus flavus[…]